What are the causes of blisters on the base of the foot?

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Blisters are described as small bubbles filled with fluid that manifest right under the skin. These blisters are considered as the common cause of pain in the foot especially among runners. It is important to note that blisters typically develop on the base of the foot but can also occur along the sides or top area. An injury to the skin or certain disease can cause the upper layer of the skin or epidermis to separate from the middle layer, which is the space in between the skin layers that is filled with fluid as a protective measure.

Athlete’s foot infection

If an individual has athlete’s foot or tinea pedis, it can cause small blisters to form on the base of the foot. This infection develops once a particular type of fungus grows on the skin. These usually thrive in moist and warm parts of the body, especially the feet. The skin will form miniature blisters that are itchy at first and then crack open, resulting to a crusty rash. The condition can be treated with several over-the-counter antifungal medications.

In most cases, a blister develops due to friction and pressure by wearing shoes that are too tight or constant rubbing.


In most cases, a blister develops due to friction and pressure by wearing shoes that are too tight or constant rubbing. A blister contains clear fluid but if there is injury, it can contain blood.


Take note that burns can also cause blisters to develop. In case the blister was caused by a burn and becomes infected, it can contain pus. The treatment typically includes keeping the blister clean and even releasing the fluid to reduce the pain. If you want to learn how to properly manage burns, click here.

Contact dermatitis

Contact dermatitis can cause the development of small blisters on the base of the foot as a response to an allergic reaction. Dyes and chemicals utilized in the manufacturing of socks and shoes, fragrances in soaps and detergents and even some oral and topical medications can lead to blister formation. Take note that blisters can also form as a reaction to poison ivy if the base of the foot was exposed. The treatment includes application of calamine lotion as well as oral or topical antihistamines.

Dyshidrotic eczema

Dyshidrotic eczema is a skin condition that results to small blisters to develop on the base of the feet and palms of the hands. Eczema is quite common among women than men. Blisters which become severely itchy can last up to 3 weeks and are quite common during certain times of the year particularly among those who suffer from seasonal allergies. The blisters can crack open as they heal, leaving behind patches of dry, scaly skin. The treatment includes steroid creams and oral antihistamines.

Other possible causes

There are also other conditions that can cause the formation of blisters to develop on the base of the foot. Take note that hand, foot and mouth disease is a viral disease that is seen in some children. Along with the blisters on the base of the feet, there are also blisters on the hands and sores in the mouth.

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